Sugar acids and derivatives
Medchemexpress LLC Diethylstilbestrol-d8 | 91318-10-4 | MFCD01074086 | 99.7% | C18H12D8O2 | 10MG
Diethylstilbestrol-d8 is the deuterium-labeled analogue of diethylstilbestrol supplied as a high-purity powder for research and analytical use. It is intended as a stable isotope internal standard for LC-MS, pharmacokinetic studies, and quantitative assays where mass differentiation from the parent compound is required.
- High isotopic purity suitable for mass spectrometry internal standard.
- Purity 99.7% as supplied.
- Molecular formula C18H12D8O2 and molecular weight 276.40.
- Recommended solvent: DMSO, 50 mg/mL with ultrasonic and warming.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Supplied in small research pack sizes appropriate for analytical workflows.
Medchemexpress LLC IFN-beta Protein, Rhesus Macaque (HEK293, Fc) | ≥ 85% | Approximately 45-56 kDa | 50 UG
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family. It reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway and regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration. This specific product is a recombinant Rhesus Macaque-derived IFN-beta protein, expressed by HEK293, with a C-mFc labeled tag.
- Immunomodulatory cytokine of the type 1 interferon family.
- Reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway.
- Regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration.
Medchemexpress LLC D-Mannoheptulose | 3615-44-9 | MFCD00006622 | 210.18 | 10 MG
D-Mannoheptulose is a 7-carbon keto sugar found in avocado. It is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. This compound can block insulin release and the utilization of carbohydrates in rats. It also exhibits various functions such as antioxidant and anticancer effects, and can act as an energy source.
- Specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes
- Can block insulin release
- Can block utilization of carbohydrates in rats
- Exhibits antioxidant effects
- Shows anticancer effects
- Acts as an energy source
- Inhibits breast cancer cell line growth (MCF-7 IC50: 263.3 μg/mL)
- No significant cytotoxic effect on normal cells (HMECs IC50: 975.1 μg/mL)
![Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 100 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661682.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy B D glucopyranoside [4 Methylumbelliferyl N acetyl B D glucosaminide], 100 Milligrams
Methylumbelliferyl Glucosaminide is a high-purity biochemical reagent used in various analytical applications, particularly in biochemical analysis. This 100mg preparation is commonly used for evaluating enzyme activities that involve glucosamine-based substrates. It is frequently employed in studies of glycosaminoglycan metabolism and glycosyltransferase reactions, offering reliable, reproducible results in enzyme-linked assays. This reagent has a broad range of applications, including use in metabolic studies, cell culture experiments, and in testing the enzymatic breakdown of glucosamine derivatives. It is an essential tool for laboratories conducting research in biochemistry, molecular biology, and pharmacology.
Medchemexpress LLC Rose-β-D-Gal | 138182-21-5 | MFCD01310928 | 99.7% | 329.73 g/mol | C14H16ClNO6 | 10 MG
Rose-β-D-Gal is a chromogenic substrate for β-galactosidase that produces a pink/magenta color upon enzymatic cleavage. It exhibits fluorescent properties (excitation 488 nm and emission 540 nm), is supplied as a white to off-white solid, and is intended for biochemical and cell-based assays to detect β-gal activity.
- Chromogenic substrate for β-galactosidase detection.
- Produces a pink/magenta color upon enzymatic cleavage.
- Excitation 488 nm and emission 540 nm for fluorescence-based assays.
- High purity suitable for analytical and research applications.
- Solid form for easy weighing and storage.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Medchemexpress LLC Integrin alpha 8 bet 100ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Integrin alpha X bet 10ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
![Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237008.png-250.jpg)
Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG
BET-BAY 002 is a research-grade small-molecule BET bromodomain inhibitor used in epigenetic and oncology research. It is supplied as a white to off-white solid (CAS 1588521-78-1) with a molecular weight of 403.86 g/mol and reported high purity for reliable experimental use. The compound dissolves readily in DMSO and has recommended storage conditions for long-term stability.
Medchemexpress LLC IFN-beta Rhesus Mac 50ug
IFN-beta Protein Rhesus Macaque (HEK293 Fc Solution) is the recombinant rhesus macaque-derived IFN-beta protein expressed by HEK293 with C-mFc tag
Medchemexpress LLC Bet bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 g/mol | C24H20ClN5O2 | 100 MG
BET bromodomain inhibitor is a small-molecule research compound that selectively inhibits BET family bromodomains, including BRD4, with reported biochemical potency (BRD4(1) IC50 = 14 nM). It is supplied as a solid (white to off-white) with high purity for preclinical laboratory use.
- Potent BRD4 inhibitor (IC50 = 14 nM).
- High purity (~99.5%).
- Solid, white to off-white powder.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small research quantities, including 100 MG packaging.
Medchemexpress LLC IL-18RAP Rhesus Mac 5ug | 5ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 500 MG
MAC glucuronide linker-1 is a cleavable glucuronide-based linker developed for constructing antibody-drug conjugates (ADCs) in research applications. It is supplied as a solid with reported high purity and specific storage recommendations for stability.
- Cleavable glucuronide-based linker suitable for ADC construction.
- Reported purity 96.36% (typical).
- Molecular weight 897.90 g/mol.
- Chemical formula C42H47N3O17S.
- Supplied as a powder; multiple package sizes available.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human therapeutic use.
Medchemexpress LLC Msx-127 (NSC-23026) | 6616-56-4 | MFCD00087356 | 99.7% | 308.37 g/mol | C16H24N2O4 | 25 MG
MSX-127 is a small-molecule C-X-C chemokine receptor 4 (CXCR4) antagonist supplied for research use. It inhibits CXCR4-mediated signaling and has been used in studies of cancer metastasis. The compound is provided as a high-purity solid with documented storage and solubility properties suitable for in vitro research applications.
- Acts as a CXCR4 antagonist relevant to cancer and immunology research.
- High reported purity (≈99.68%).
- Molecular weight 308.37 g/mol and formula C16H24N2O4.
- White to off-white solid appearance.
- Soluble in DMSO (≈41.67 mg/mL); ultrasonic assistance may be required.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).